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SEMINARSKI RAD
DIZAJNIRANJE LIJEKOVA
TEMA: Sintetski postupci i razvoj novih lijekova
Profesor: Student:
Prof.dr
Brčko,2016 .g.
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Sadržaj:
1.UVOD.....................................................................................................................3
2.SINTETSKI POSTUPCI........................................................................................4
2.1 Aspirin.................................................................................................................4
2.2 Salicilna kiselina.................................................................................................5
2.3 Sinteza aspirina...................................................................................................5
3.PRONALAZAK I RAZVOJ NOVIH LIJEKOVA...............................................6
3.1 Pretklinički razvoj lijeka.....................................................................................6
3.1.1 I FAZA.............................................................................................................6
3.1.2 II FAZA…………………………………………………………………....…6
3.1.3 III FAZA...........................................................................................................7
3.1.4 IV FAZA.......................................................................................................... 7
4.2 kliničko ispitivanje lijeka………..……………………………………………..7
4.2.1 I FAZA.............................................................................................................7
4.2.2 II FAZA............................................................................................................ 8
4.3.3 III FAZA...........................................................................................................8
4.4.4 IV FAZA.......................................................................................................... 8
5.ZAKLJUČAK……………………………………………………………………9
6.LITERATURA………………………………………………………………….10
